Desloratadine

desloratadine
Indications:
Desloratadine is indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis.
Availability:
          Desloratadine is available in film-coated tablets contains desloratadine 5mg. it’s also available in syrup in 120ml. each ml contain 0.5mg desloratadine.
Description:      
Desloratadine is non sedating long active histamine antagonist.
Clinical pharmacology:
Desloratadine is long-acting tricyclic histamine antagonist with selective H1  receptor. It inhibits histamine release from human mast cells.
Absorption:
it is absorbed with maximum PMC approximately,
excretion:
 the mean elimination half-life of was 27 hours.
 Side effects:

It is contraindicated in patients who have shone hypersensitivity to desloratadine. In nursing mothers, desloratadine passes into human breastmilk. 

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